ACHIEVEMENTS / 项目成果

Research with a wider impact.

Research programs, clinical guidance, and translational contributions.

Research funding

2016–2018

NSFC Young Scientists Fund 81500464

Led by Yu Shi, this project studied how myeloid-derived suppressor cells regulate monocyte and macrophage function in cirrhosis complicated by sepsis.

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2019–2022

NSFC General Program 81870425

Led by Yu Shi, this project investigated the origin, functional properties, and role of TREM-2-positive hepatic macrophages in liver failure.

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2018–present

National Key R&D and Major Science Programs

Principal investigator of three NSFC grants and task leader in two studies under the National Key R&D Program / National Science and Technology Major Projects.

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Guidelines & consensus

2024

Guideline for Diagnosis and Treatment of Liver Failure (2024)

Yu Shi served on the expert group and as a drafting author for the updated definitions, classification, diagnosis, and treatment recommendations.

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2025

ACLF Kyoto Consensus: Steps from Asia

As a co-author of this international consensus, Yu Shi contributed to aligning ACLF definitions, stratification, and research frameworks across Asia.

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Awards

2018

Second Prize, Zhejiang Natural Science Award

The award recognized foundational research on viral-hepatitis mechanisms and outcome prediction; Yu Shi was the fourth listed contributor.

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2023

World’s Top 2% Scientists

Selected for the 2023 edition of the World’s Top 2% Scientists list.

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Zhejiang Provincial High-Level Health Talent

Recognized as a high-level health talent in Zhejiang Province.

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Outstanding Young Clinical Talent, Zhejiang University School of Medicine

Selected as an outstanding young clinical talent by Zhejiang University School of Medicine.

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Patents

2021

Granted invention patent CN110655566B

Preparation and application of soluble Tim-3 recombinant and mutant proteins; owned by Zhejiang University, with Yu Shi as a co-inventor.

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2023

Granted invention patent CN111783792B

A method and application for extracting salient texture features from ultrasound images; owned by Zhejiang University, with Yu Shi as a co-inventor.

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